The methanolic extract of Chlorophytum borivilianum Sant & Fern. root tubers (MECB) was screened for hepatoprotective effect in carbon tetrachloride ( CCl4 ) induced hepatotoxicity in albino rats. The degree of protection was measured by estimating an increase in biochemical parameters like serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminse (SGPT), total protein and level of serum biliruibin (both total and direct). Hepatoprotective activity of methanolic extract at a dose of 400 mg / kg body weight, p.o .was compared with silymarin (100 mg /kg, p.o.) treated animals. Methanolic extract of Chlorophytum borivilianum root tubers ( 200 mg /kg & 400 mg /kg) exhibited significant reduction in serum hepatic enzymes when compared to rats treated with carbon tetrachloride alone.
Loading....